Annotating New Genes: From in Silico Screening to Experimental Validation Author: S Uchida | Language: English | ISBN:
1907568689 | Format: EPUB
Annotating New Genes: From in Silico Screening to Experimental Validation Description
In recent years, a number of academic and commercial software packages and databases have been developed for the analysis and screening of biological data; however, the usability of these data is compromised by so-called novel genes to which no biological function is assigned. Annotating new genes outlines an approach to the analysis of evolutionary-conserved, heart-enriched genes with unknown functions, offering a step-by-step description of the procedure from screening to validation. The book begins by offering an introduction to the databases and software available, before moving on to cover programming guidelines, including a specific case study on the use of C-It for in silico screening. The second half of the book offers a step-by-step guide to experimental validation concepts and procedures, as well as an overview of additional potential applications of this approach in the field of stem cells and tissue regeneration, before a concluding chapter summarises the concepts and theories presented.
- Focuses not only on screening but also on biological validations
- Provides details of databases and software (web interface) products for biologists with minimal computation skills
- Offers a step-by-step outline of the procedure involved
- Series: Woodhead Publishing Series in Biomedicine
- Hardcover: 196 pages
- Publisher: Woodhead Publishing; 1 edition (August 20, 2012)
- Language: English
- ISBN-10: 1907568689
- ISBN-13: 978-1907568688
- Product Dimensions: 9.2 x 6.1 x 0.5 inches
- Shipping Weight: 1.3 pounds (View shipping rates and policies)
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